BDBM329882 (rac)-((1R,2R,3S,4R)-2,3-dihydroxy-4-(2-(3-(2-propoxypropan-2-::US10202389, Compound I-090::US9663525, Compound I-090::US9796725, Compound I-090

SMILES: CCCOC(C)(C)c1cccc(c1)-c1cc2nccc(N[C@@H]3C[C@H](COS(N)(=O)=O)[C@@H](O)[C@H]3O)n2n1

InChI Key: InChIKey=NKWYEVDNDOILAN-SAVREHANSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 329882   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E2 ubiquitin-conjugating enzyme E1 (Homo sapiens (Human))	BDBM329882 ((rac)-((1R,2R,3S,4R)-2,3-dihydroxy-4-(2-(3-(2-prop...) Show SMILES CCCOC(C)(C)c1cccc(c1)-c1cc2nccc(N[C@@H]3C[C@H](COS(N)(=O)=O)[C@@H](O)[C@H]3O)n2n1 |r| Show InChI InChI=1S/C24H33N5O6S/c1-4-10-34-24(2,3)17-7-5-6-15(11-17)18-13-21-26-9-8-20(29(21)28-18)27-19-12-16(22(30)23(19)31)14-35-36(25,32)33/h5-9,11,13,16,19,22-23,27,30-31H,4,10,12,14H2,1-3H3,(H2,25,32,33)/t16-,19-,22-,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description The UAE enzymatic reaction totals 50 μL and contains 50 mmol HEPES (pH 7.5), 0.05% BSA, 2.5 mM MgCl2, 0.1 uM ATP, 8 nM GST-Ubc-2, 35 nM flag-ubi...				US Patent US9663525 (2017) BindingDB Entry DOI: 10.7270/Q2HM5BJP
					More data for this Ligand-Target Pair
SUMO-activating enzyme subunit 2 (SAE2) (Homo sapiens (Human))	BDBM329882 ((rac)-((1R,2R,3S,4R)-2,3-dihydroxy-4-(2-(3-(2-prop...) Show SMILES CCCOC(C)(C)c1cccc(c1)-c1cc2nccc(N[C@@H]3C[C@H](COS(N)(=O)=O)[C@@H](O)[C@H]3O)n2n1 |r| Show InChI InChI=1S/C24H33N5O6S/c1-4-10-34-24(2,3)17-7-5-6-15(11-17)18-13-21-26-9-8-20(29(21)28-18)27-19-12-16(22(30)23(19)31)14-35-36(25,32)33/h5-9,11,13,16,19,22-23,27,30-31H,4,10,12,14H2,1-3H3,(H2,25,32,33)/t16-,19-,22-,23+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description he UAE enzymatic reaction totals 50 μL and contains 50 mmol HEPES (pH 7.5), 0.05% BSA, 2.5 mM MgCl2, 0.1 uM ATP, 8 nM GST-Ubc-2, 35 nM flag-ubiq...				US Patent US9796725 (2017) BindingDB Entry DOI: 10.7270/Q23T9KC6
					More data for this Ligand-Target Pair
Ubiquitin-like modifier-activating enzyme 1 (Homo sapiens (Human))	BDBM329882 ((rac)-((1R,2R,3S,4R)-2,3-dihydroxy-4-(2-(3-(2-prop...) Show SMILES CCCOC(C)(C)c1cccc(c1)-c1cc2nccc(N[C@@H]3C[C@H](COS(N)(=O)=O)[C@@H](O)[C@H]3O)n2n1 |r| Show InChI InChI=1S/C24H33N5O6S/c1-4-10-34-24(2,3)17-7-5-6-15(11-17)18-13-21-26-9-8-20(29(21)28-18)27-19-12-16(22(30)23(19)31)14-35-36(25,32)33/h5-9,11,13,16,19,22-23,27,30-31H,4,10,12,14H2,1-3H3,(H2,25,32,33)/t16-,19-,22-,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description The UAE enzymatic reaction totals 50 μL and contains 50 mmol HEPES (pH 7.5), 0.05% BSA, 2.5 mM MgCl2, 0.1 uM ATP, 8 nM GST-Ubc-2, 35 nM flag-ubi...				US Patent US10202389 (2019) BindingDB Entry DOI: 10.7270/Q2DN475J
					More data for this Ligand-Target Pair