BDBM330344 US9724435, Compound CM-356

SMILES: CC(=O)c1ccc2oc(=O)n(CCCCN3CCN(CC3)c3ccc(F)cc3)c2c1

InChI Key: InChIKey=NIKCPKNTCKAENL-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330344   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma-2 receptor (Rattus norvegicus (Rat))	BDBM330344 (US9724435, Compound CM-356) Show SMILES CC(=O)c1ccc2oc(=O)n(CCCCN3CCN(CC3)c3ccc(F)cc3)c2c1 Show InChI InChI=1S/C23H26FN3O3/c1-17(28)18-4-9-22-21(16-18)27(23(29)30-22)11-3-2-10-25-12-14-26(15-13-25)20-7-5-19(24)6-8-20/h4-9,16H,2-3,10-15H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY US Patent					Assay Description Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...				US Patent US9724435 (2017) BindingDB Entry DOI: 10.7270/Q2BZ6856
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM330344 (US9724435, Compound CM-356) Show SMILES CC(=O)c1ccc2oc(=O)n(CCCCN3CCN(CC3)c3ccc(F)cc3)c2c1 Show InChI InChI=1S/C23H26FN3O3/c1-17(28)18-4-9-22-21(16-18)27(23(29)30-22)11-3-2-10-25-12-14-26(15-13-25)20-7-5-19(24)6-8-20/h4-9,16H,2-3,10-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	27.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY US Patent					Assay Description Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...				US Patent US9724435 (2017) BindingDB Entry DOI: 10.7270/Q2BZ6856
					More data for this Ligand-Target Pair