BDBM33061 4-N,4-N-dimethyl-1-N-(4-pyridin-3-yl-1,3-thiazol-2-yl)benzene-1,4-diamine::MLS000108847::N4,N4-dimethyl-N1-(4-pyridin-3-yl-1,3-thiazol-2-yl)benzene-1,4-diamine::N4,N4-dimethyl-N1-[4-(3-pyridinyl)-2-thiazolyl]benzene-1,4-diamine::SMR000104797::cid_704601::dimethyl-[4-[[4-(3-pyridyl)thiazol-2-yl]amino]phenyl]amine
SMILES: CN(C)c1ccc(Nc2nc(cs2)-c2cccnc2)cc1
InChI Key: InChIKey=VQQBVGGMFGFZPI-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bcl-2-related protein A1 (Homo sapiens (Human)) | BDBM33061 (4-N,4-N-dimethyl-1-N-(4-pyridin-3-yl-1,3-thiazol-2...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | n/a | 850 | n/a | n/a | 7.4 | 4 |
NMMLSC Curated by PubChem BioAssay | Assay Description The multiplex is constructed by using beads for each protein target that have been labeled with varying intensities of red color, so that each assay ... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2CN728N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM33061 (4-N,4-N-dimethyl-1-N-(4-pyridin-3-yl-1,3-thiazol-2...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | n/a | 6.75E+4 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,... | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2ZP44SP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
large T antigen (Simian virus 40) | BDBM33061 (4-N,4-N-dimethyl-1-N-(4-pyridin-3-yl-1,3-thiazol-2...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | 8.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Specialized Biocontainment Screening Center Curated by PubChem BioAssay | Assay Description A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2M61HQ8 | |||||||||||
More data for this Ligand-Target Pair |