null
SMILES: Cc1cc(ccn1)-c1ccc(s1)C(=O)N[C@@H](C1CCCCC1)C(=O)N1C[C@H](Cl)[C@H]2OCC(=O)[C@@H]12
InChI Key: InChIKey=WOLBGFZLMWKIDO-AIZKBTNYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cathepsin K (Homo sapiens (Human)) | BDBM331568 (N-((S)-2-((3aS,6S,6aS)-6-chloro-3- oxotetrahydro-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GRUNENTHAL GMBH US Patent | Assay Description Recombinant human cathepsins (CatS, CatK, CatL) were purchased from a Enzo Life Sciences. All assays were carried out in 96-well format using a buffe... | US Patent US9725459 (2017) BindingDB Entry DOI: 10.7270/Q2JH3P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin S (Homo sapiens (Human)) | BDBM331568 (N-((S)-2-((3aS,6S,6aS)-6-chloro-3- oxotetrahydro-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 86 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GRUNENTHAL GMBH US Patent | Assay Description Recombinant human cathepsins (CatS, CatK, CatL) were purchased from a Enzo Life Sciences. All assays were carried out in 96-well format using a buffe... | US Patent US9725459 (2017) BindingDB Entry DOI: 10.7270/Q2JH3P8R | |||||||||||
More data for this Ligand-Target Pair |