null
SMILES: CC1(C)CCC2(CCC3(C)C(C2C1)C(=O)C=C1C2(C)C=C(C#N)C(=O)C(C)(C)C2CCC31C)C(=O)n1cnc(c1)-c1cccnc1
InChI Key: InChIKey=GXKRPLQWYWDFQN-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nitric oxide synthase, inducible (Homo sapiens (Human)) | BDBM331833 (US10189791, CDDO-3P-Im 3) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Trustees of Dartmouth College US Patent | Assay Description Because oxidative and inflammatory stress contribute to carcinogenesis (Albini & Sporn (2007) Nature Rev. Cancer 7:139-147), it was determined whethe... | US Patent US10189791 (2019) BindingDB Entry DOI: 10.7270/Q2571F3P | |||||||||||
More data for this Ligand-Target Pair |