BDBM332044 (E)-N'-[(2- hydroxynaphthalen-1- yl)methylene]-2-{N-{2-[N- (4-cyanobenzyl)-N- methylamino]ethyl}N- methylamino}acethydrazide::US10196346, Example 26

SMILES: CN(CCN(C)Cc1ccc(cc1)C#N)CC(=O)N\N=C\c1c(O)ccc2ccccc12

InChI Key: InChIKey=LUYOTZBVLKPKBP-JVWAILMASA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332044   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM332044 ((E)-N'-[(2- hydroxynaphthalen-1- yl)methylene]-2-{...) Show SMILES CN(CCN(C)Cc1ccc(cc1)C#N)CC(=O)N\N=C\c1c(O)ccc2ccccc12 Show InChI InChI=1S/C25H27N5O2/c1-29(17-20-9-7-19(15-26)8-10-20)13-14-30(2)18-25(32)28-27-16-23-22-6-4-3-5-21(22)11-12-24(23)31/h3-12,16,31H,13-14,17-18H2,1-2H3,(H,28,32)/b27-16+	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	980	n/a	n/a	n/a	n/a
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China US Patent					Assay Description The compounds were formulated with DMSO to form 30 mM stock solutions, and then formulated with analytical nutrient solution to form 2× working solut...				US Patent US10196346 (2019) BindingDB Entry DOI: 10.7270/Q2VQ34SQ
					More data for this Ligand-Target Pair