BDBM33236 thieno[2,3-d]pyrimidine, 34c

SMILES: CCN(CC)CCOc1cc(c(Cl)cc1Cl)-c1nc(N)nc2sc(cc12)C(=O)NCC(F)(F)F

InChI Key: InChIKey=QYZCJVOCSJBEHM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 33236   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heat shock protein HSP 90-beta (Homo sapiens (Human))	BDBM33236 (thieno[2,3-d]pyrimidine, 34c) Show SMILES CCN(CC)CCOc1cc(c(Cl)cc1Cl)-c1nc(N)nc2sc(cc12)C(=O)NCC(F)(F)F Show InChI InChI=1S/C21H22Cl2F3N5O2S/c1-3-31(4-2)5-6-33-15-7-11(13(22)9-14(15)23)17-12-8-16(18(32)28-10-21(24,25)26)34-19(12)30-20(27)29-17/h7-9H,3-6,10H2,1-2H3,(H,28,32)(H2,27,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	7.4	23
Vernalis (R&D) Ltd					Assay Description The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...				J Med Chem 52: 4794-809 (2009) Article DOI: 10.1021/jm900357y BindingDB Entry DOI: 10.7270/Q2445JVZ
					More data for this Ligand-Target Pair