BDBM332546 (2E)-1-{7-[(2E)-3-(4-bromophenyl)prop-2-enoyl]-2,7-diazaspiro[3.5]non-2-yl}-3-(4-bromophenyl)prop-2-en-1-one::US10196369, Compound C1

SMILES: Brc1ccc(\C=C\C(=O)N2CC3(C2)CCN(CC3)C(=O)\C=C\c2ccc(Br)cc2)cc1

InChI Key: InChIKey=PPWLCGUEYORUON-YDWXAUTNSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332546   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332546 ((2E)-1-{7-[(2E)-3-(4-bromophenyl)prop-2-enoyl]-2,7...) Show SMILES Brc1ccc(\C=C\C(=O)N2CC3(C2)CCN(CC3)C(=O)\C=C\c2ccc(Br)cc2)cc1 Show InChI InChI=1S/C25H24Br2N2O2/c26-21-7-1-19(2-8-21)5-11-23(30)28-15-13-25(14-16-28)17-29(18-25)24(31)12-6-20-3-9-22(27)10-4-20/h1-12H,13-18H2/b11-5+,12-6+	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair