BDBM332550 5-chloroindol-2-yl 2-[(4-fluorophenyl)carbonyl]-2,7-diazaspiro[3.5]non-7-yl ketone::US10196369, Compound C5

SMILES: Fc1ccc(cc1)C(=O)N1CC2(C1)CCN(CC2)C(=O)c1cc2cc(Cl)ccc2[nH]1

InChI Key: InChIKey=XPXHQTSYOPXLSN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332550   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332550 (5-chloroindol-2-yl 2-[(4-fluorophenyl)carbonyl]-2,...) Show SMILES Fc1ccc(cc1)C(=O)N1CC2(C1)CCN(CC2)C(=O)c1cc2cc(Cl)ccc2[nH]1 Show InChI InChI=1S/C23H21ClFN3O2/c24-17-3-6-19-16(11-17)12-20(26-19)22(30)27-9-7-23(8-10-27)13-28(14-23)21(29)15-1-4-18(25)5-2-15/h1-6,11-12,26H,7-10,13-14H2	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair