BDBM332555 (2E)-1-{2-[(3,5-dichlorophenyl)carbonyl]-2,7-diazaspiro[3.5]non-7-yl}-3-(4-bromophenyl)prop-2-en-1-one::US10196369, Compound C10

SMILES: Clc1cc(Cl)cc(c1)C(=O)N1CC2(C1)CCN(CC2)C(=O)\C=C\c1ccc(Br)cc1

InChI Key: InChIKey=MHFVLAGNURYUAI-ZZXKWVIFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332555   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332555 ((2E)-1-{2-[(3,5-dichlorophenyl)carbonyl]-2,7-diaza...) Show SMILES Clc1cc(Cl)cc(c1)C(=O)N1CC2(C1)CCN(CC2)C(=O)\C=C\c1ccc(Br)cc1 Show InChI InChI=1S/C23H21BrCl2N2O2/c24-18-4-1-16(2-5-18)3-6-21(29)27-9-7-23(8-10-27)14-28(15-23)22(30)17-11-19(25)13-20(26)12-17/h1-6,11-13H,7-10,14-15H2/b6-3+	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair