BDBM332556 (2E)-1-{2-[(2,6-dichlorophenyl)methyl]-2,7-diazaspiro[3.5]non-7-yl}-3-(4-bromophenyl)prop-2-en-1-one::US10196369, Compound C11

SMILES: Clc1cccc(Cl)c1CN1CC2(C1)CCN(CC2)C(=O)\C=C\c1ccc(Br)cc1

InChI Key: InChIKey=ULOWIVDVXARWCW-RMKNXTFCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332556   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332556 ((2E)-1-{2-[(2,6-dichlorophenyl)methyl]-2,7-diazasp...) Show SMILES Clc1cccc(Cl)c1CN1CC2(C1)CCN(CC2)C(=O)\C=C\c1ccc(Br)cc1 Show InChI InChI=1S/C23H23BrCl2N2O/c24-18-7-4-17(5-8-18)6-9-22(29)28-12-10-23(11-13-28)15-27(16-23)14-19-20(25)2-1-3-21(19)26/h1-9H,10-16H2/b9-6+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair