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SMILES: Clc1ccc(cc1)C(=O)N1CCC2(CN(C2)C(=O)c2cc3cc(Cl)ccc3[nH]2)CC1

InChI Key: InChIKey=KHIQQXASZYUWHZ-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332585   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
G-protein coupled receptor 183


(Homo sapiens (Human))		BDBM332585
PNG
(5-chloroindol-2-yl 7-[(4-chlorophenyl)carbonyl]-2,...)
Show SMILES Clc1ccc(cc1)C(=O)N1CCC2(CN(C2)C(=O)c2cc3cc(Cl)ccc3[nH]2)CC1
Show InChI InChI=1S/C23H21Cl2N3O2/c24-17-3-1-15(2-4-17)21(29)27-9-7-23(8-10-27)13-28(14-23)22(30)20-12-16-11-18(25)5-6-19(16)26-20/h1-6,11-12,26H,7-10,13-14H2
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
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UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE

US Patent


Assay Description
The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...

US Patent US10196369 (2019)


BindingDB Entry DOI: 10.7270/Q2BR8V88
More data for this
Ligand-Target Pair