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SMILES: Fc1ccc(C(=O)N2CC3(C2)CCN(CC3)C(=O)\C=C\c2ccc(Br)cc2)c(c1)C(F)(F)F

InChI Key: InChIKey=PQZBFRYMNKABGI-FPYGCLRLSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332597   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
G-protein coupled receptor 183


(Homo sapiens (Human))		BDBM332597
PNG
((2E)-3-(4-bromophenyl)-1-(2-{[4-fluoro-2-(trifluor...)
Show SMILES Fc1ccc(C(=O)N2CC3(C2)CCN(CC3)C(=O)\C=C\c2ccc(Br)cc2)c(c1)C(F)(F)F
Show InChI InChI=1S/C24H21BrF4N2O2/c25-17-4-1-16(2-5-17)3-8-21(32)30-11-9-23(10-12-30)14-31(15-23)22(33)19-7-6-18(26)13-20(19)24(27,28)29/h1-8,13H,9-12,14-15H2/b8-3+
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
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UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE

US Patent


Assay Description
The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...

US Patent US10196369 (2019)


BindingDB Entry DOI: 10.7270/Q2BR8V88
More data for this
Ligand-Target Pair