BDBM332613 3-(4-bromophenyl)-1-{2-[(4-fluorophenyl)methyl]-2,7-diazaspiro[3.5]non-7-yl}prop-2-yn-1-one::US10196369, Compound C68

SMILES: Fc1ccc(CN2CC3(C2)CCN(CC3)C(=O)C#Cc2ccc(Br)cc2)cc1

InChI Key: InChIKey=KAJAZDHHGSYRIX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332613   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 183 (Homo sapiens (Human))	BDBM332613 (3-(4-bromophenyl)-1-{2-[(4-fluorophenyl)methyl]-2,...) Show SMILES Fc1ccc(CN2CC3(C2)CCN(CC3)C(=O)C#Cc2ccc(Br)cc2)cc1 Show InChI InChI=1S/C23H22BrFN2O/c24-20-6-1-18(2-7-20)5-10-22(28)27-13-11-23(12-14-27)16-26(17-23)15-19-3-8-21(25)9-4-19/h1-4,6-9H,11-17H2	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...				US Patent US10196369 (2019) BindingDB Entry DOI: 10.7270/Q2BR8V88
					More data for this Ligand-Target Pair