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BDBM33264 guanidine, 4

SMILES: [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-1-[#6](=O)-[#7]-c2ccccc-12

InChI Key: InChIKey=OQLWRGUXLSZBEX-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 33264   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Trypsin


(Bos taurus (bovine))
BDBM33264
PNG
(guanidine, 4)
Show SMILES [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-1-[#6](=O)-[#7]-c2ccccc-12 |w:4.3|
Show InChI InChI=1S/C9H9N5O/c10-9(11)14-13-7-5-3-1-2-4-6(5)12-8(7)15/h1-4H,(H4,10,11,14)(H,12,13,15)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
4.00E+3 -7.31n/an/an/an/an/a7.623



University of Alabama at Birmingham



Assay Description
All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...


Bioorg Med Chem 13: 257-64 (2005)


Article DOI: 10.1016/j.bmc.2004.09.036
BindingDB Entry DOI: 10.7270/Q2QV3JVQ
More data for this
Ligand-Target Pair
West Nile Virus (WNV) NS2B-NS3 Protease


(West Nile virus (WNV))
BDBM33264
PNG
(guanidine, 4)
Show SMILES [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-1-[#6](=O)-[#7]-c2ccccc-12 |w:4.3|
Show InChI InChI=1S/C9H9N5O/c10-9(11)14-13-7-5-3-1-2-4-6(5)12-8(7)15/h1-4H,(H4,10,11,14)(H,12,13,15)
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
1.60E+4 -6.49n/an/an/an/an/a8.523



University of Alabama at Birmingham



Assay Description
All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...


Bioorg Med Chem 13: 257-64 (2005)


Article DOI: 10.1016/j.bmc.2004.09.036
BindingDB Entry DOI: 10.7270/Q2QV3JVQ
More data for this
Ligand-Target Pair
Dengue Virus 2 (DENV2) NS2B-NS3 Protease


(Dengue virus 2 (strain TSV01))
BDBM33264
PNG
(guanidine, 4)
Show SMILES [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-1-[#6](=O)-[#7]-c2ccccc-12 |w:4.3|
Show InChI InChI=1S/C9H9N5O/c10-9(11)14-13-7-5-3-1-2-4-6(5)12-8(7)15/h1-4H,(H4,10,11,14)(H,12,13,15)
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
2.30E+4 -6.28n/an/an/an/an/a8.523



University of Alabama at Birmingham



Assay Description
All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...


Bioorg Med Chem 13: 257-64 (2005)


Article DOI: 10.1016/j.bmc.2004.09.036
BindingDB Entry DOI: 10.7270/Q2QV3JVQ
More data for this
Ligand-Target Pair