BDBM333028 US10196391, Example 28

SMILES: COc1cc(cc(F)c1F)N1CCc2nc(ncc2C1)-c1cnccn1

InChI Key: InChIKey=YWHWIEJJDDSMRT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333028   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepatitis GB virus B)	BDBM333028 (US10196391, Example 28) Show SMILES COc1cc(cc(F)c1F)N1CCc2nc(ncc2C1)-c1cnccn1 Show InChI InChI=1S/C18H15F2N5O/c1-26-16-7-12(6-13(19)17(16)20)25-5-2-14-11(10-25)8-23-18(24-14)15-9-21-3-4-22-15/h3-4,6-9H,2,5,10H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	455	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...				US Patent US10196391 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HNM
					More data for this Ligand-Target Pair