BDBM333042 US10196391, Example 42

SMILES: Fc1cc(cc(c1)N1CCc2nc(ncc2C1)-c1ncccn1)C1CC1

InChI Key: InChIKey=ZVCVGMRQGIMJKG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333042   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis GB virus B NS5B RNA-dependent RNA polymerase (Hepatitis GB virus B)	BDBM333042 (US10196391, Example 42) Show SMILES Fc1cc(cc(c1)N1CCc2nc(ncc2C1)-c1ncccn1)C1CC1 Show InChI InChI=1S/C20H18FN5/c21-16-8-14(13-2-3-13)9-17(10-16)26-7-4-18-15(12-26)11-24-20(25-18)19-22-5-1-6-23-19/h1,5-6,8-11,13H,2-4,7,12H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	566	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...				US Patent US10196391 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HNM
					More data for this Ligand-Target Pair