BDBM333093 US10196391, Example 93

SMILES: OCCCOc1cc(cc(F)c1F)N1CCc2nc(ncc2C1)-c1ccccn1

InChI Key: InChIKey=VVQLAEWTYDFJFO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333093   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis GB virus B NS5B RNA-dependent RNA polymerase (Hepatitis GB virus B)	BDBM333093 (US10196391, Example 93) Show SMILES OCCCOc1cc(cc(F)c1F)N1CCc2nc(ncc2C1)-c1ccccn1 Show InChI InChI=1S/C21H20F2N4O2/c22-16-10-15(11-19(20(16)23)29-9-3-8-28)27-7-5-17-14(13-27)12-25-21(26-17)18-4-1-2-6-24-18/h1-2,4,6,10-12,28H,3,5,7-9,13H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	314	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...				US Patent US10196391 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HNM
					More data for this Ligand-Target Pair