BDBM334277 N-(2-Bromo-pyridin- 4-yl)-2-hydroxy- 2-methyl-4-phenyl- butyramide::US9732044, 43

SMILES: CC(O)(CCc1ccccc1)C(=O)Nc1ccnc(Br)c1

InChI Key: InChIKey=PXNNPZDHXHIUML-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 334277   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM334277 (N-(2-Bromo-pyridin- 4-yl)-2-hydroxy- 2-methyl-4-ph...) Show SMILES CC(O)(CCc1ccccc1)C(=O)Nc1ccnc(Br)c1 Show InChI InChI=1S/C16H17BrN2O2/c1-16(21,9-7-12-5-3-2-4-6-12)15(20)19-13-8-10-18-14(17)11-13/h2-6,8,10-11,21H,7,9H2,1H3,(H,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides described herein exhibit androgen receptor (AR) inhibiting properties. This AR inhibiting activ...				US Patent US9732044 (2017) BindingDB Entry DOI: 10.7270/Q2348NHJ
					More data for this Ligand-Target Pair