BDBM335698 (R)-3-(3-Methyl-2-oxopiperidin-3-yl)-6-(5-methylquinolin-3-yl)pyridin-2(1H)-one::US9738626, 1 (free base)

SMILES: Cc1cccc2ncc(cc12)-c1ccc(c(=O)[nH]1)[C@@]1(C)CCCNC1=O

InChI Key: InChIKey=OJVNYQOKTZLPPX-OAQYLSRUSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 335698   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM335698 ((R)-3-(3-Methyl-2-oxopiperidin-3-yl)-6-(5-methylqu...) Show SMILES Cc1cccc2ncc(cc12)-c1ccc(c(=O)[nH]1)[C@@]1(C)CCCNC1=O Show InChI InChI=1S/C21H21N3O2/c1-13-5-3-6-18-15(13)11-14(12-23-18)17-8-7-16(19(25)24-17)21(2)9-4-10-22-20(21)26/h3,5-8,11-12H,4,9-10H2,1-2H3,(H,22,26)(H,24,25)/t21-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description To measure the ability of test compounds in the present invention to bind to the human EP3 receptor, and therefore have the potential to antagonize P...				US Patent US9738626 (2017) BindingDB Entry DOI: 10.7270/Q2CF9S7K
					More data for this Ligand-Target Pair