BDBM335704 (R)-3-(3-Methyl-2-oxopyrrolidin-3-yl)-6-(5-methylquinolin-3-yl)pyridin-2(1H)-one::US9738626, 7 (formate salt)
SMILES: Cc1cccc2ncc(cc12)-c1ccc(c(=O)[nH]1)[C@@]1(C)CCNC1=O
InChI Key: InChIKey=NYMPHOZUBJYHBQ-HXUWFJFHSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human)) | BDBM335704 ((R)-3-(3-Methyl-2-oxopyrrolidin-3-yl)-6-(5-methylq...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 18.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description To measure the ability of test compounds in the present invention to bind to the human EP3 receptor, and therefore have the potential to antagonize P... | US Patent US9738626 (2017) BindingDB Entry DOI: 10.7270/Q2CF9S7K | |||||||||||
More data for this Ligand-Target Pair |