null

SMILES: CC(=O)N1CCc2cc(cc(F)c12)-c1cnccc1C

InChI Key: InChIKey=FQAXMQBKAVFFGA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 336520   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM336520 (1-(7-fluoro-5-(4- methylpyridin-3- yl)indolin-1-yl...) Show SMILES CC(=O)N1CCc2cc(cc(F)c12)-c1cnccc1C Show InChI InChI=1S/C16H15FN2O/c1-10-3-5-18-9-14(10)13-7-12-4-6-19(11(2)20)16(12)15(17)8-13/h3,5,7-9H,4,6H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp; ElexoPharm GmbH US Patent									US Patent US9745282 (2017) BindingDB Entry DOI: 10.7270/Q25Q4Z66
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM336520 (1-(7-fluoro-5-(4- methylpyridin-3- yl)indolin-1-yl...) Show SMILES CC(=O)N1CCc2cc(cc(F)c12)-c1cnccc1C Show InChI InChI=1S/C16H15FN2O/c1-10-3-5-18-9-14(10)13-7-12-4-6-19(11(2)20)16(12)15(17)8-13/h3,5,7-9H,4,6H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp; ElexoPharm GmbH US Patent					Assay Description V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...				US Patent US9745282 (2017) BindingDB Entry DOI: 10.7270/Q25Q4Z66
					More data for this Ligand-Target Pair