null

SMILES: OC(CNC(=O)COc1ccccc1S(=O)(=O)N1CCCC1)CN1CCc2ccccc2C1

InChI Key: InChIKey=UZCKDZZDYLVHEC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 337064   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM337064 (US9745291, Compound 110 | US9765068, Compound 110) Show SMILES OC(CNC(=O)COc1ccccc1S(=O)(=O)N1CCCC1)CN1CCc2ccccc2C1 Show InChI InChI=1S/C24H31N3O5S/c28-21(17-26-14-11-19-7-1-2-8-20(19)16-26)15-25-24(29)18-32-22-9-3-4-10-23(22)33(30,31)27-12-5-6-13-27/h1-4,7-10,21,28H,5-6,11-18H2,(H,25,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description Molecular Biology: Full-length human PRMT5 (NM_006109.3) transcript variant 1 clone was amplified from a fetal brain cDNA library, incorporating flan...				US Patent US9765068 (2017) BindingDB Entry DOI: 10.7270/Q2959KN3
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM337064 (US9745291, Compound 110 | US9765068, Compound 110) Show SMILES OC(CNC(=O)COc1ccccc1S(=O)(=O)N1CCCC1)CN1CCc2ccccc2C1 Show InChI InChI=1S/C24H31N3O5S/c28-21(17-26-14-11-19-7-1-2-8-20(19)16-26)15-25-24(29)18-32-22-9-3-4-10-23(22)33(30,31)27-12-5-6-13-27/h1-4,7-10,21,28H,5-6,11-18H2,(H,25,29)	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US9745291 (2017) BindingDB Entry DOI: 10.7270/Q2J1058K
					More data for this Ligand-Target Pair