BDBM337155 US9745291, Compound 201

SMILES: CNCCN(C)S(=O)(=O)c1ccccc1OCC(=O)NC[C@@H](O)CN1CCc2ccccc2C1

InChI Key: InChIKey=RPWKJRCUXIFXLH-OAQYLSRUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337155   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PRMT5/MEP50 Enzyme (Homo sapiens (Human))	BDBM337155 (US9745291, Compound 201) Show SMILES CNCCN(C)S(=O)(=O)c1ccccc1OCC(=O)NC[C@@H](O)CN1CCc2ccccc2C1 |r| Show InChI InChI=1S/C24H34N4O5S/c1-25-12-14-27(2)34(31,32)23-10-6-5-9-22(23)33-18-24(30)26-15-21(29)17-28-13-11-19-7-3-4-8-20(19)16-28/h3-10,21,25,29H,11-18H2,1-2H3,(H,26,30)/t21-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US9745291 (2017) BindingDB Entry DOI: 10.7270/Q2J1058K
					More data for this Ligand-Target Pair