BDBM337156 US9745291, Compound 202

SMILES: CC1CNCCN1S(=O)(=O)c1ccccc1OCC(=O)NC[C@@H](O)CN1CCc2ccccc2C1

InChI Key: InChIKey=AJPWAHUWWVTOLT-AVKWCDSFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337156   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PRMT5/MEP50 Enzyme (Homo sapiens (Human))	BDBM337156 (US9745291, Compound 202) Show SMILES CC1CNCCN1S(=O)(=O)c1ccccc1OCC(=O)NC[C@@H](O)CN1CCc2ccccc2C1 |r| Show InChI InChI=1S/C25H34N4O5S/c1-19-14-26-11-13-29(19)35(32,33)24-9-5-4-8-23(24)34-18-25(31)27-15-22(30)17-28-12-10-20-6-2-3-7-21(20)16-28/h2-9,19,22,26,30H,10-18H2,1H3,(H,27,31)/t19?,22-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US9745291 (2017) BindingDB Entry DOI: 10.7270/Q2J1058K
					More data for this Ligand-Target Pair