BDBM337374 6-[4-(2,3-Dihydro-1H-pyrrolo[3,2-c]pyridin-4-yloxy)phenyl]-1,5-dimethylpyrimidine-2,4(1H,3H)-dione (12)::US9745317, 12

SMILES: Cc1c(-c2ccc(Oc3nccc4NCCc34)cc2)n(C)c(=O)[nH]c1=O

InChI Key: InChIKey=VHTXUSXOCGZBMT-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337374   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM337374 (6-[4-(2,3-Dihydro-1H-pyrrolo[3,2-c]pyridin-4-yloxy...) Show SMILES Cc1c(-c2ccc(Oc3nccc4NCCc34)cc2)n(C)c(=O)[nH]c1=O Show InChI InChI=1S/C19H18N4O3/c1-11-16(23(2)19(25)22-17(11)24)12-3-5-13(6-4-12)26-18-14-7-9-20-15(14)8-10-21-18/h3-6,8,10,20H,7,9H2,1-2H3,(H,22,24,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	11.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...				US Patent US9745317 (2017) BindingDB Entry DOI: 10.7270/Q2W95CBQ
					More data for this Ligand-Target Pair