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BDBM337375 6-[4-(2,3-Dihydrofuro[3,2-c]pyridin-4-yloxy)phenyl]-1,5-dimethylpyrimidine-2,4(1H,3H)-dione, trifluoroacetate salt (13)::US9745317, 13

SMILES: Cc1c(-c2ccc(Oc3nccc4OCCc34)cc2)n(C)c(=O)[nH]c1=O

InChI Key: InChIKey=QPLJZRMOGQVJOB-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337375   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D(1A) dopamine receptor


(Homo sapiens (Human))
BDBM337375
PNG
(6-[4-(2,3-Dihydrofuro[3,2-c]pyridin-4-yloxy)phenyl...)
Show SMILES Cc1c(-c2ccc(Oc3nccc4OCCc34)cc2)n(C)c(=O)[nH]c1=O
Show InChI InChI=1S/C19H17N3O4/c1-11-16(22(2)19(24)21-17(11)23)12-3-5-13(6-4-12)26-18-14-8-10-25-15(14)7-9-20-18/h3-7,9H,8,10H2,1-2H3,(H,21,23,24)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
46.1n/an/an/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...


US Patent US9745317 (2017)


BindingDB Entry DOI: 10.7270/Q2W95CBQ
More data for this
Ligand-Target Pair