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BDBM337380 US9745317, 18

SMILES: Cc1cc(Oc2nccc3OCCc23)ccc1-c1c(C)ncc2nccn12

InChI Key: InChIKey=KHMWDJLBLWMDFH-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337380   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(1A) dopamine receptor


(Homo sapiens (Human))		BDBM337380
PNG
(US9745317, 18)
Show SMILES Cc1cc(Oc2nccc3OCCc23)ccc1-c1c(C)ncc2nccn12 |(-.05,4.23,;-.05,2.69,;-1.39,1.92,;-1.39,.38,;-2.72,-.39,;-2.72,-1.93,;-1.39,-2.7,;-1.39,-4.24,;-2.72,-5.01,;-4.06,-4.24,;-5.52,-4.71,;-6.43,-3.47,;-5.52,-2.22,;-4.06,-2.7,;-.05,-.38,;1.28,.38,;1.28,1.92,;2.61,2.7,;2.61,4.24,;1.28,5.01,;3.95,5,;5.28,4.24,;5.28,2.7,;6.43,1.66,;5.8,.26,;4.27,.42,;3.95,1.93,)|
Show InChI InChI=1S/C21H18N4O2/c1-13-11-15(27-21-17-6-10-26-18(17)5-7-23-21)3-4-16(13)20-14(2)24-12-19-22-8-9-25(19)20/h3-5,7-9,11-12H,6,10H2,1-2H3
PDB

KEGG

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PC cid
PC sid
UniChem
US Patent
 52.1n/an/an/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...

US Patent US9745317 (2017)


BindingDB Entry DOI: 10.7270/Q2W95CBQ
More data for this
Ligand-Target Pair