null

SMILES: CC1CCN(CC1)C(=O)c1cc(cnc1N)-c1ccnc(NC(C)=O)c1

InChI Key: InChIKey=GQKIWDYVDIPTFX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 337900   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337900 (US9751854, Compound I-81 | US9802960, Compound I-8...) Show SMILES CC1CCN(CC1)C(=O)c1cc(cnc1N)-c1ccnc(NC(C)=O)c1 Show InChI InChI=1S/C19H23N5O2/c1-12-4-7-24(8-5-12)19(26)16-9-15(11-22-18(16)20)14-3-6-21-17(10-14)23-13(2)25/h3,6,9-12H,4-5,7-8H2,1-2H3,(H2,20,22)(H,21,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9802960 (2017) BindingDB Entry DOI: 10.7270/Q2D79DJ9
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337900 (US9751854, Compound I-81 | US9802960, Compound I-8...) Show SMILES CC1CCN(CC1)C(=O)c1cc(cnc1N)-c1ccnc(NC(C)=O)c1 Show InChI InChI=1S/C19H23N5O2/c1-12-4-7-24(8-5-12)19(26)16-9-15(11-22-18(16)20)14-3-6-21-17(10-14)23-13(2)25/h3,6,9-12H,4-5,7-8H2,1-2H3,(H2,20,22)(H,21,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair