null

SMILES: CN(C)S(=O)(=O)c1cc(cnc1N)-c1ccnc(NC(C)=O)c1

InChI Key: InChIKey=CUSNPYAULLUKDQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 337943   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337943 (US9751854, Compound I-119 | US9802960, Compound I-...) Show SMILES CN(C)S(=O)(=O)c1cc(cnc1N)-c1ccnc(NC(C)=O)c1 Show InChI InChI=1S/C14H17N5O3S/c1-9(20)18-13-7-10(4-5-16-13)11-6-12(14(15)17-8-11)23(21,22)19(2)3/h4-8H,1-3H3,(H2,15,17)(H,16,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9802960 (2017) BindingDB Entry DOI: 10.7270/Q2D79DJ9
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337943 (US9751854, Compound I-119 | US9802960, Compound I-...) Show SMILES CN(C)S(=O)(=O)c1cc(cnc1N)-c1ccnc(NC(C)=O)c1 Show InChI InChI=1S/C14H17N5O3S/c1-9(20)18-13-7-10(4-5-16-13)11-6-12(14(15)17-8-11)23(21,22)19(2)3/h4-8H,1-3H3,(H2,15,17)(H,16,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair