null

SMILES: CC(=O)Nc1cc(ccn1)-c1cnc(C)c(NS(=O)(=O)c2ccccc2F)c1

InChI Key: InChIKey=SWGXMZDIVBXUFZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 337968   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337968 (US9751854, Compound I-144 | US9802960, Compound I-...) Show SMILES CC(=O)Nc1cc(ccn1)-c1cnc(C)c(NS(=O)(=O)c2ccccc2F)c1 Show InChI InChI=1S/C19H17FN4O3S/c1-12-17(24-28(26,27)18-6-4-3-5-16(18)20)9-15(11-22-12)14-7-8-21-19(10-14)23-13(2)25/h3-11,24H,1-2H3,(H,21,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9802960 (2017) BindingDB Entry DOI: 10.7270/Q2D79DJ9
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337968 (US9751854, Compound I-144 | US9802960, Compound I-...) Show SMILES CC(=O)Nc1cc(ccn1)-c1cnc(C)c(NS(=O)(=O)c2ccccc2F)c1 Show InChI InChI=1S/C19H17FN4O3S/c1-12-17(24-28(26,27)18-6-4-3-5-16(18)20)9-15(11-22-12)14-7-8-21-19(10-14)23-13(2)25/h3-11,24H,1-2H3,(H,21,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair