BDBM338404 (3S,6R)-2-[[2-fluoro-4-[(3S,4R)-3- methoxy-4-(1,2,4-triazol-4-yl)-1- piperidyl]phenyl]methyl]-3-methyl- 6-phenyl-thiazinane 1,1-dioxide::US9751873, Example 92

SMILES: CO[C@H]1CN(CC[C@H]1n1cnnc1)c1ccc(CN2[C@@H](C)CC[C@H](c3ccccc3)S2(=O)=O)c(F)c1

InChI Key: InChIKey=CLOJABNEIVSCFJ-QNMIOERPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 338404   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM338404 ((3S,6R)-2-[[2-fluoro-4-[(3S,4R)-3- methoxy-4-(1,2,...) Show SMILES CO[C@H]1CN(CC[C@H]1n1cnnc1)c1ccc(CN2[C@@H](C)CC[C@H](c3ccccc3)S2(=O)=O)c(F)c1 |r| Show InChI InChI=1S/C26H32FN5O3S/c1-19-8-11-26(20-6-4-3-5-7-20)36(33,34)32(19)15-21-9-10-22(14-23(21)27)30-13-12-24(25(16-30)35-2)31-17-28-29-18-31/h3-7,9-10,14,17-19,24-26H,8,11-13,15-16H2,1-2H3/t19-,24+,25-,26+/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.60	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...				US Patent US9751873 (2017) BindingDB Entry DOI: 10.7270/Q2BC41NZ
					More data for this Ligand-Target Pair