BindingDB logo
myBDB logout

null

SMILES: C[C@H]1CC[C@H](c2ccccc2)S(=O)(=O)N1Cc1cc(F)c(cc1F)N1CC[C@H]([C@@H](F)C1)n1cnnc1

InChI Key: InChIKey=SQCNQJLVQLTVSN-XXWQXCTJSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 338424   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))		BDBM338424
PNG
((3S,6R)-2-[[2,5-difluoro-4-[(3S,4R)- 3-fluoro-4-[(...)
Show SMILES C[C@H]1CC[C@H](c2ccccc2)S(=O)(=O)N1Cc1cc(F)c(cc1F)N1CC[C@H]([C@@H](F)C1)n1cnnc1 |r|
Show InChI InChI=1S/C25H28F3N5O2S/c1-17-7-8-25(18-5-3-2-4-6-18)36(34,35)33(17)13-19-11-21(27)24(12-20(19)26)31-10-9-23(22(28)14-31)32-15-29-30-16-32/h2-6,11-12,15-17,22-23,25H,7-10,13-14H2,1H3/t17-,22-,23+,25+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 13n/an/an/an/an/an/a



Genentech, Inc.

US Patent


Assay Description
Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...

US Patent US9751873 (2017)


BindingDB Entry DOI: 10.7270/Q2BC41NZ
More data for this
Ligand-Target Pair