BDBM33955 dihydroxy benzoyl naphthyl hydrazone (DHBNH) analogue, 2

SMILES: COc1ccc2ccccc2c1\C=N\NC(=O)c1ccc(C)cc1

InChI Key: InChIKey=UAEMIAMYLRWYFF-FYJGNVAPSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 33955   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HIV-1 Reverse Transcriptase RNase H (Human immunodeficiency virus type 1)	BDBM33955 (dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...) Show SMILES COc1ccc2ccccc2c1\C=N\NC(=O)c1ccc(C)cc1 Show InChI InChI=1S/C20H18N2O2/c1-14-7-9-16(10-8-14)20(23)22-21-13-18-17-6-4-3-5-15(17)11-12-19(18)24-2/h3-13H,1-2H3,(H,22,23)/b21-13+	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	7.8	37
Rutgers University					Assay Description HIV-1 RT RDDP activity was generally determined by a fixed time assay. Briefly, reaction mixtures contained p51/p66 RT, template-primer, and [3H]-TTP...				ACS Chem Biol 1: 702-12 (2006) Article DOI: 10.1021/cb600303y BindingDB Entry DOI: 10.7270/Q2FF3QQC
					More data for this Ligand-Target Pair
HIV-1 Reverse Transcriptase RNase H (Human immunodeficiency virus type 1)	BDBM33955 (dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...) Show SMILES COc1ccc2ccccc2c1\C=N\NC(=O)c1ccc(C)cc1 Show InChI InChI=1S/C20H18N2O2/c1-14-7-9-16(10-8-14)20(23)22-21-13-18-17-6-4-3-5-15(17)11-12-19(18)24-2/h3-13H,1-2H3,(H,22,23)/b21-13+	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	8.0	37
Rutgers University					Assay Description To assess the effect of inhibitors, RT RNH activity was measured using a FRET-based microplate fluorescence assay. Briefly, the RNA-DNA hybrid duplex...				ACS Chem Biol 1: 702-12 (2006) Article DOI: 10.1021/cb600303y BindingDB Entry DOI: 10.7270/Q2FF3QQC
					More data for this Ligand-Target Pair