null

SMILES: COc1ccc2ccccc2c1\C=N\NC(=O)C1CCC(CC1)c1ccc(Cl)cc1

InChI Key: InChIKey=NYSSHZUZNGBACC-JVWAILMASA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 33961   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S] (Human immunodeficiency virus type 1)	BDBM33961 (dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...) Show SMILES COc1ccc2ccccc2c1\C=N\NC(=O)C1CCC(CC1)c1ccc(Cl)cc1 |(-7.76,3.32,;-9.3,3.33,;-10.06,4.66,;-11.6,4.67,;-12.37,6,;-11.59,7.34,;-12.36,8.67,;-11.58,10,;-10.04,10,;-9.28,8.66,;-10.05,7.33,;-9.29,5.99,;-7.75,5.99,;-6.98,4.66,;-5.44,4.66,;-4.67,3.33,;-5.44,1.99,;-3.13,3.33,;-2.3,4.63,;-.76,4.56,;-.05,3.2,;-.87,1.9,;-2.41,1.96,;1.49,3.14,;2.2,4.51,;3.74,4.57,;4.57,3.28,;6.11,3.34,;3.86,1.91,;2.32,1.84,)| Show InChI InChI=1S/C25H25ClN2O2/c1-30-24-15-12-19-4-2-3-5-22(19)23(24)16-27-28-25(29)20-8-6-17(7-9-20)18-10-13-21(26)14-11-18/h2-5,10-17,20H,6-9H2,1H3,(H,28,29)/b27-16+	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	7.8	37
Rutgers University					Assay Description HIV-1 RT RDDP activity was generally determined by a fixed time assay. Briefly, reaction mixtures contained p51/p66 RT, template-primer, and [3H]-TTP...				ACS Chem Biol 1: 702-12 (2006) Article DOI: 10.1021/cb600303y BindingDB Entry DOI: 10.7270/Q2FF3QQC
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S] (Human immunodeficiency virus type 1)	BDBM33961 (dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...) Show SMILES COc1ccc2ccccc2c1\C=N\NC(=O)C1CCC(CC1)c1ccc(Cl)cc1 |(-7.76,3.32,;-9.3,3.33,;-10.06,4.66,;-11.6,4.67,;-12.37,6,;-11.59,7.34,;-12.36,8.67,;-11.58,10,;-10.04,10,;-9.28,8.66,;-10.05,7.33,;-9.29,5.99,;-7.75,5.99,;-6.98,4.66,;-5.44,4.66,;-4.67,3.33,;-5.44,1.99,;-3.13,3.33,;-2.3,4.63,;-.76,4.56,;-.05,3.2,;-.87,1.9,;-2.41,1.96,;1.49,3.14,;2.2,4.51,;3.74,4.57,;4.57,3.28,;6.11,3.34,;3.86,1.91,;2.32,1.84,)| Show InChI InChI=1S/C25H25ClN2O2/c1-30-24-15-12-19-4-2-3-5-22(19)23(24)16-27-28-25(29)20-8-6-17(7-9-20)18-10-13-21(26)14-11-18/h2-5,10-17,20H,6-9H2,1H3,(H,28,29)/b27-16+	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	8.0	37
Rutgers University					Assay Description To assess the effect of inhibitors, RT RNH activity was measured using a FRET-based microplate fluorescence assay. Briefly, the RNA-DNA hybrid duplex...				ACS Chem Biol 1: 702-12 (2006) Article DOI: 10.1021/cb600303y BindingDB Entry DOI: 10.7270/Q2FF3QQC
					More data for this Ligand-Target Pair