BDBM340398 US9758538, Example 86
SMILES: Nc1ncc(cn1)-c1cc(N[C@@]2(CO)CCN(C2)C(=O)c2ncc[nH]2)nc(n1)N1CCOCC1
InChI Key:
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PI3-kinase class I (Homo sapiens (Human)) | BDBM340398 (US9758538, Example 86) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
PFIZER INC. US Patent | Assay Description The biochemical assays of kinase activity of full-length PI3Kα (full-length p110α/p85α) or truncated PI3Kα (p110α/iSH2 p85... | US Patent US9758538 (2017) BindingDB Entry DOI: 10.7270/Q27D2X70 | |||||||||||
More data for this Ligand-Target Pair |