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BDBM34055 iodinated benzimidazole, 21

SMILES: OC(=O)Cn1cnc2c(I)c(I)c(I)c(I)c12

InChI Key: InChIKey=SMEROVWVAAPMQO-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 34055   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Casein kinase II subunit alpha


(Homo sapiens (Human))
BDBM34055
PNG
(iodinated benzimidazole, 21)
Show SMILES OC(=O)Cn1cnc2c(I)c(I)c(I)c(I)c12
Show InChI InChI=1S/C9H4I4N2O2/c10-4-5(11)7(13)9-8(6(4)12)14-2-15(9)1-3(16)17/h2H,1H2,(H,16,17)
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62n/an/an/an/an/an/an/an/a



The John Paul II Catholic University of Lublin

Curated by ChEMBL


Assay Description
Inhibition of human CK2 alpha' catalytic subunit expressed in Escherichia coli BL21 (DE3) assessed as [33P]gamma-ATP incorporation into P2B substrate...


Eur J Med Chem 47: 345-50 (2012)


Article DOI: 10.1016/j.ejmech.2011.11.002
More data for this
Ligand-Target Pair
Casein Kinase II


(Rattus norvegicus (Rat))
BDBM34055
PNG
(iodinated benzimidazole, 21)
Show SMILES OC(=O)Cn1cnc2c(I)c(I)c(I)c(I)c12
Show InChI InChI=1S/C9H4I4N2O2/c10-4-5(11)7(13)9-8(6(4)12)14-2-15(9)1-3(16)17/h2H,1H2,(H,16,17)
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140 -9.72n/an/an/an/an/a7.537



University of Padova



Assay Description
Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w...


Bioorg Med Chem 17: 7281-9 (2009)


Article DOI: 10.1016/j.bmc.2009.08.047
More data for this
Ligand-Target Pair
Casein kinase II alpha


(Homo sapiens (Human))
BDBM34055
PNG
(iodinated benzimidazole, 21)
Show SMILES OC(=O)Cn1cnc2c(I)c(I)c(I)c(I)c12
Show InChI InChI=1S/C9H4I4N2O2/c10-4-5(11)7(13)9-8(6(4)12)14-2-15(9)1-3(16)17/h2H,1H2,(H,16,17)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
261n/an/an/an/an/an/an/an/a



The John Paul II Catholic University of Lublin

Curated by ChEMBL


Assay Description
Inhibition of human CK2 alpha catalytic subunit expressed in Escherichia coli BL21 (DE3) assessed as [33P]gamma-ATP incorporation into RRRADDSDDDDD s...


Eur J Med Chem 47: 345-50 (2012)


Article DOI: 10.1016/j.ejmech.2011.11.002
More data for this
Ligand-Target Pair
Casein kinase II subunit alpha


(Homo sapiens (Human))
BDBM34055
PNG
(iodinated benzimidazole, 21)
Show SMILES OC(=O)Cn1cnc2c(I)c(I)c(I)c(I)c12
Show InChI InChI=1S/C9H4I4N2O2/c10-4-5(11)7(13)9-8(6(4)12)14-2-15(9)1-3(16)17/h2H,1H2,(H,16,17)
PDB
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PC cid
PC sid
UniChem
Article
PubMed
324n/an/an/an/an/an/an/an/a



The John Paul II Catholic University of Lublin

Curated by ChEMBL


Assay Description
Inhibition of human CK2 alpha' catalytic subunit expressed in Escherichia coli BE21 (DE3) assessed as [33P]gamma-ATP incorporation into RRRADDSDDDDD ...


Eur J Med Chem 47: 345-50 (2012)


Article DOI: 10.1016/j.ejmech.2011.11.002
More data for this
Ligand-Target Pair
Casein kinase II alpha


(Homo sapiens (Human))
BDBM34055
PNG
(iodinated benzimidazole, 21)
Show SMILES OC(=O)Cn1cnc2c(I)c(I)c(I)c(I)c12
Show InChI InChI=1S/C9H4I4N2O2/c10-4-5(11)7(13)9-8(6(4)12)14-2-15(9)1-3(16)17/h2H,1H2,(H,16,17)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
378n/an/an/an/an/an/an/an/a



The John Paul II Catholic University of Lublin

Curated by ChEMBL


Assay Description
Inhibition of human CK2 alpha catalytic subunit expressed in Escherichia coli BE21 (DE3) assessed as [33P]gamma-ATP incorporation into P2B substrate ...


Eur J Med Chem 47: 345-50 (2012)


Article DOI: 10.1016/j.ejmech.2011.11.002
More data for this
Ligand-Target Pair