BDBM34072 benzamide derivative, 12

SMILES: Cn1ccnc1Sc1cc(C(=O)Nc2cccc(N)c2)c(N)cc1F

InChI Key: InChIKey=XZUOXUGTBFDKKR-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 34072   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human))	BDBM34072 (benzamide derivative, 12) Show SMILES Cn1ccnc1Sc1cc(C(=O)Nc2cccc(N)c2)c(N)cc1F Show InChI InChI=1S/C17H16FN5OS/c1-23-6-5-21-17(23)25-15-8-12(14(20)9-13(15)18)16(24)22-11-4-2-3-10(19)7-11/h2-9H,19-20H2,1H3,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a
Shanghai Institutes for Biological Sciences					Assay Description The GK activity was assessed spectrometrically by a coupled reaction with glucose-6-phosphate dehydrogenase (G6PDH). Briefly, GK catalyzes glucose ph...				Bioorg Med Chem 17: 7301-12 (2009) Article DOI: 10.1016/j.bmc.2009.08.045 BindingDB Entry DOI: 10.7270/Q2DF6PK0
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGM) (Oryctolagus cuniculus (rabbit))	BDBM34072 (benzamide derivative, 12) Show SMILES Cn1ccnc1Sc1cc(C(=O)Nc2cccc(N)c2)c(N)cc1F Show InChI InChI=1S/C17H16FN5OS/c1-23-6-5-21-17(23)25-15-8-12(14(20)9-13(15)18)16(24)22-11-4-2-3-10(19)7-11/h2-9H,19-20H2,1H3,(H,22,24)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.68E+3	n/a	n/a	n/a	n/a	7.2	22
Shanghai Institutes for Biological Sciences					Assay Description The enzymatic inhibition of phosphorylase activity was monitored using microplate reader (Bio-Rad). In brief, GPa activity was measured in the direct...				Bioorg Med Chem 17: 7301-12 (2009) Article DOI: 10.1016/j.bmc.2009.08.045 BindingDB Entry DOI: 10.7270/Q2DF6PK0
					More data for this Ligand-Target Pair