BDBM340731 US9763922, Example 257

SMILES: Cn1cc(cn1)-c1cc(F)c(Nc2nn([C@H]3CCOC3)c3CCN(Cc23)C(N)=O)cc1C(F)F

InChI Key: InChIKey=STSVDECZAMJHLX-ZDUSSCGKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 340731   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM340731 (US9763922, Example 257) Show SMILES Cn1cc(cn1)-c1cc(F)c(Nc2nn([C@H]3CCOC3)c3CCN(Cc23)C(N)=O)cc1C(F)F |r| Show InChI InChI=1S/C22H24F3N7O2/c1-30-9-12(8-27-30)14-6-17(23)18(7-15(14)20(24)25)28-21-16-10-31(22(26)33)4-2-19(16)32(29-21)13-3-5-34-11-13/h6-9,13,20H,2-5,10-11H2,1H3,(H2,26,33)(H,28,29)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...				US Patent US9763922 (2017) BindingDB Entry DOI: 10.7270/Q23N25G6
					More data for this Ligand-Target Pair
CREB-binding protein (Homo sapiens (Human))	BDBM340731 (US9763922, Example 257) Show SMILES Cn1cc(cn1)-c1cc(F)c(Nc2nn([C@H]3CCOC3)c3CCN(Cc23)C(N)=O)cc1C(F)F |r| Show InChI InChI=1S/C22H24F3N7O2/c1-30-9-12(8-27-30)14-6-17(23)18(7-15(14)20(24)25)28-21-16-10-31(22(26)33)4-2-19(16)32(29-21)13-3-5-34-11-13/h6-9,13,20H,2-5,10-11H2,1H3,(H2,26,33)(H,28,29)/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...				US Patent US9763922 (2017) BindingDB Entry DOI: 10.7270/Q23N25G6
					More data for this Ligand-Target Pair