BDBM34098 benzamide derivative, 14b

SMILES: Fc1ccccc1N1CCN(CC(=O)Nc2cccc(c2)C(F)(F)F)CC1

InChI Key: InChIKey=BCIUYVKYSDASDK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 34098   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human))	BDBM34098 (benzamide derivative, 14b) Show SMILES Fc1ccccc1N1CCN(CC(=O)Nc2cccc(c2)C(F)(F)F)CC1 Show InChI InChI=1S/C19H19F4N3O/c20-16-6-1-2-7-17(16)26-10-8-25(9-11-26)13-18(27)24-15-5-3-4-14(12-15)19(21,22)23/h1-7,12H,8-11,13H2,(H,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institutes for Biological Sciences					Assay Description The GK activity was assessed spectrometrically by a coupled reaction with glucose-6-phosphate dehydrogenase (G6PDH). Briefly, GK catalyzes glucose ph...				Bioorg Med Chem 17: 7301-12 (2009) Article DOI: 10.1016/j.bmc.2009.08.045 BindingDB Entry DOI: 10.7270/Q2DF6PK0
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGM) (Oryctolagus cuniculus (rabbit))	BDBM34098 (benzamide derivative, 14b) Show SMILES Fc1ccccc1N1CCN(CC(=O)Nc2cccc(c2)C(F)(F)F)CC1 Show InChI InChI=1S/C19H19F4N3O/c20-16-6-1-2-7-17(16)26-10-8-25(9-11-26)13-18(27)24-15-5-3-4-14(12-15)19(21,22)23/h1-7,12H,8-11,13H2,(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.85E+4	n/a	n/a	n/a	n/a	7.2	22
Shanghai Institutes for Biological Sciences					Assay Description The enzymatic inhibition of phosphorylase activity was monitored using microplate reader (Bio-Rad). In brief, GPa activity was measured in the direct...				Bioorg Med Chem 17: 7301-12 (2009) Article DOI: 10.1016/j.bmc.2009.08.045 BindingDB Entry DOI: 10.7270/Q2DF6PK0
					More data for this Ligand-Target Pair