BindingDB PrimarySearch

BDBM34103 D-glucose::dextrose::glucose

SMILES: OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O

InChI Key: InChIKey=WQZGKKKJIJFFOK-GASJEMHNSA-N

Data: 7 KI

PDB links: 245 PDB IDs match this monomer. 440 PDB IDs contain this monomer as substructures. 440 PDB IDs contain inhibitors having a similarity of 90% to this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 34103
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Lipopolysaccharide heptosyltransferase 1 (Escherichia coli (strain K12))	BDBM34103 (D-glucose \| dextrose \| glucose) Show SMILES OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.80E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wesleyan University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli Heptosyltransferase I assessed as reduction in ADP release using ODLA and ADP-heptose substrates in presence of phosph...				Bioorg Med Chem Lett 28: 594-600 (2018) Article DOI: 10.1016/j.bmcl.2018.01.040 BindingDB Entry DOI: 10.7270/Q2J38W63
Wesleyan University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscle glycogen phosphorylase (Homo sapiens (Human))	BDBM34103 (D-glucose \| dextrose \| glucose) Show SMILES OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.70E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Alcala Curated by ChEMBL					Assay Description Inhibitory activity against rabbit muscle glycogen phosphorylase				J Med Chem 40: 4089-102 (1998) Checked by Author Article DOI: 10.1021/jm970273d BindingDB Entry DOI: 10.7270/Q2S46TGM
University of Alcala Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Brain glycogen phosphorylase (Homo sapiens (Human))	BDBM34103 (D-glucose \| dextrose \| glucose) Show SMILES OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.70E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of rabbit glycogen phosphorylase B enzyme				J Med Chem 40: 1455-64 (1997) Article DOI: 10.1021/jm9608016 BindingDB Entry DOI: 10.7270/Q26T0N9N
University of Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Brain glycogen phosphorylase (Homo sapiens (Human))	BDBM34103 (D-glucose \| dextrose \| glucose) Show SMILES OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	7.40E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Debrecen Curated by ChEMBL					Assay Description Inhibitory activity against muscle Glycogen Phosphorylase b				J Med Chem 44: 2843-8 (2001) BindingDB Entry DOI: 10.7270/Q2NV9JZQ
University of Debrecen Curated by ChEMBL					More data for this Ligand-Target Pair
Brain glycogen phosphorylase (Homo sapiens (Human))	BDBM34103 (D-glucose \| dextrose \| glucose) Show SMILES OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	7.40E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibitory binding constant against glycogen phosphorylase B				J Med Chem 47: 3075-88 (2004) Article DOI: 10.1021/jm030586a BindingDB Entry DOI: 10.7270/Q2930TXG
The University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Brain glycogen phosphorylase (Homo sapiens (Human))	BDBM34103 (D-glucose \| dextrose \| glucose) Show SMILES OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.26E+11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps-Universit£t Marburg Curated by ChEMBL					Assay Description Inhibitory activity against Pig Skeletal Glycogen Phosphorylase b				J Med Chem 45: 4153-70 (2002) Article DOI: 10.1021/jm020808p BindingDB Entry DOI: 10.7270/Q2KH0R3H
Philipps-Universit£t Marburg Curated by ChEMBL					More data for this Ligand-Target Pair
Brain glycogen phosphorylase (Homo sapiens (Human))	BDBM34103 (D-glucose \| dextrose \| glucose) Show SMILES OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	6.31E+11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps-Universit£t Marburg Curated by ChEMBL					Assay Description Inhibitory activity against Pig Skeletal Glycogen Phosphorylase b				J Med Chem 45: 4153-70 (2002) Article DOI: 10.1021/jm020808p BindingDB Entry DOI: 10.7270/Q2KH0R3H
Philipps-Universit£t Marburg Curated by ChEMBL					More data for this Ligand-Target Pair