BDBM341154 US9765058, Example 2-2-2
SMILES: CCOC(=O)c1cnccc1Nc1ccnc(n1)-c1nn(Cc2c(F)cc(OCC)cc2F)c(C2CC2)c1Cl
InChI Key: InChIKey=DNGFKYIFNLTJNN-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitotic checkpoint serine/threonine-protein kinase BUB1 (Homo sapiens (Human)) | BDBM341154 (US9765058, Example 2-2-2) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description In a typical assay 11 different concentrations of each compound (0.1 nM, 0.33 nM, 1.1 nM, 3.8 nM, 13 nM, 44 nM, 0.15 μM, 0.51 μM, 1.7 μ... | US Patent US9765058 (2017) BindingDB Entry DOI: 10.7270/Q2JQ1347 | |||||||||||
More data for this Ligand-Target Pair |