null

SMILES: COc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4C)C(C)(C)C)c4ccccc34)n2)cc(c1)S(=O)(=O)C1CC1

InChI Key: InChIKey=LUOYPPQEEBEDSR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 342103   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM342103 (1-(3-(tert-Butyl)-1-methyl-1H-pyrazol-5-yl)-3-(4-(...) Show SMILES COc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4C)C(C)(C)C)c4ccccc34)n2)cc(c1)S(=O)(=O)C1CC1 Show InChI InChI=1S/C33H35N7O5S/c1-33(2,3)28-19-29(40(4)39-28)37-32(41)36-26-12-13-27(25-9-7-6-8-24(25)26)45-30-14-15-34-31(38-30)35-20-16-21(44-5)18-23(17-20)46(42,43)22-10-11-22/h6-9,12-19,22H,10-11H2,1-5H3,(H,34,35,38)(H2,36,37,41)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
TOPIVERT PHARMA LIMITED; RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against the GSK 3-alpha enzyme isoform (Invitrogen), are evaluated by determining the level o...				US Patent US9771353 (2017) BindingDB Entry DOI: 10.7270/Q2HQ4219
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 12 (Homo sapiens (Human))	BDBM342103 (1-(3-(tert-Butyl)-1-methyl-1H-pyrazol-5-yl)-3-(4-(...) Show SMILES COc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4C)C(C)(C)C)c4ccccc34)n2)cc(c1)S(=O)(=O)C1CC1 Show InChI InChI=1S/C33H35N7O5S/c1-33(2,3)28-19-29(40(4)39-28)37-32(41)36-26-12-13-27(25-9-7-6-8-24(25)26)45-30-14-15-34-31(38-30)35-20-16-21(44-5)18-23(17-20)46(42,43)22-10-11-22/h6-9,12-19,22H,10-11H2,1-5H3,(H,34,35,38)(H2,36,37,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TOPIVERT PHARMA LIMITED; RESPIVERT LIMITED US Patent					Assay Description p38 MAPKγ: The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashio...				US Patent US9771353 (2017) BindingDB Entry DOI: 10.7270/Q2HQ4219
					More data for this Ligand-Target Pair