BDBM342204 4-[4-[4-[5-(4-chlorophenyl)-4-methyl- 1H-imidazol-2-yl]-1-piperidyl]-7H- pyrrolo[2,3-d]pyrimidin-6- yl]benzonitrile::US9771369, Compound P-3038

SMILES: Cc1nc([nH]c1-c1ccc(Cl)cc1)C1CCN(CC1)c1ncnc2[nH]c(cc12)-c1ccc(cc1)C#N

InChI Key: InChIKey=PTKQOUMYZFZNBP-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 342204   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Kit (Kit)(D816V) (Homo sapiens (Human))	BDBM342204 (4-[4-[4-[5-(4-chlorophenyl)-4-methyl- 1H-imidazol-...) Show SMILES Cc1nc([nH]c1-c1ccc(Cl)cc1)C1CCN(CC1)c1ncnc2[nH]c(cc12)-c1ccc(cc1)C#N Show InChI InChI=1S/C28H24ClN7/c1-17-25(20-6-8-22(29)9-7-20)35-26(33-17)21-10-12-36(13-11-21)28-23-14-24(34-27(23)31-16-32-28)19-4-2-18(15-30)3-5-19/h2-9,14,16,21H,10-13H2,1H3,(H,33,35)(H,31,32,34)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent					Assay Description The c-kit mutant D816V (or kinase domain thereof) is an active kinase in AlphaScreen. IC50 values are determined with respect to inhibition of c-Kit ...				US Patent US9771369 (2017) BindingDB Entry DOI: 10.7270/Q24J0H7Q
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM342204 (4-[4-[4-[5-(4-chlorophenyl)-4-methyl- 1H-imidazol-...) Show SMILES Cc1nc([nH]c1-c1ccc(Cl)cc1)C1CCN(CC1)c1ncnc2[nH]c(cc12)-c1ccc(cc1)C#N Show InChI InChI=1S/C28H24ClN7/c1-17-25(20-6-8-22(29)9-7-20)35-26(33-17)21-10-12-36(13-11-21)28-23-14-24(34-27(23)31-16-32-28)19-4-2-18(15-30)3-5-19/h2-9,14,16,21H,10-13H2,1H3,(H,33,35)(H,31,32,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent					Assay Description Assays for biochemical cell-based activity of c-kit kinase are known in the art, for example, as described in U.S. Pat. Nos. 7,498,342 and 7,846,941,...				US Patent US9771369 (2017) BindingDB Entry DOI: 10.7270/Q24J0H7Q
					More data for this Ligand-Target Pair