null

SMILES: CCOc1ccc(cc1)-c1[nH]c(nc1C)C1(C)CCN(CC1)c1ncnc2[nH]c(cc12)-c1ccc(OC)nc1

InChI Key: InChIKey=GYDSXEMGFKUFSB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 342339   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit [D816V] (Homo sapiens (Human))	BDBM342339 (4-[4-[5-(4-ethoxyphenyl)-4-methyl-1H- imidazol-2-y...) Show SMILES CCOc1ccc(cc1)-c1[nH]c(nc1C)C1(C)CCN(CC1)c1ncnc2[nH]c(cc12)-c1ccc(OC)nc1 Show InChI InChI=1S/C30H33N7O2/c1-5-39-22-9-6-20(7-10-22)26-19(2)34-29(36-26)30(3)12-14-37(15-13-30)28-23-16-24(35-27(23)32-18-33-28)21-8-11-25(38-4)31-17-21/h6-11,16-18H,5,12-15H2,1-4H3,(H,34,36)(H,32,33,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent					Assay Description The c-kit mutant D816V (or kinase domain thereof) is an active kinase in AlphaScreen. IC50 values are determined with respect to inhibition of c-Kit ...				US Patent US9771369 (2017) BindingDB Entry DOI: 10.7270/Q24J0H7Q
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM342339 (4-[4-[5-(4-ethoxyphenyl)-4-methyl-1H- imidazol-2-y...) Show SMILES CCOc1ccc(cc1)-c1[nH]c(nc1C)C1(C)CCN(CC1)c1ncnc2[nH]c(cc12)-c1ccc(OC)nc1 Show InChI InChI=1S/C30H33N7O2/c1-5-39-22-9-6-20(7-10-22)26-19(2)34-29(36-26)30(3)12-14-37(15-13-30)28-23-16-24(35-27(23)32-18-33-28)21-8-11-25(38-4)31-17-21/h6-11,16-18H,5,12-15H2,1-4H3,(H,34,36)(H,32,33,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent					Assay Description Assays for biochemical cell-based activity of c-kit kinase are known in the art, for example, as described in U.S. Pat. Nos. 7,498,342 and 7,846,941,...				US Patent US9771369 (2017) BindingDB Entry DOI: 10.7270/Q24J0H7Q
					More data for this Ligand-Target Pair