null

SMILES: COc1ccc(cn1)-c1[nH]c(nc1C)C1(C)CCN(CC1)c1ncnc2[nH]c(cc12)-c1ccc(cc1)C#N

InChI Key: InChIKey=UEKYQOCVDXDRGF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 342340   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit [D816V] (Homo sapiens (Human))	BDBM342340 (4-[4-[4-[5-(6-methoxy-3-pyridyl)-4- methyl-1H-imid...) Show SMILES COc1ccc(cn1)-c1[nH]c(nc1C)C1(C)CCN(CC1)c1ncnc2[nH]c(cc12)-c1ccc(cc1)C#N Show InChI InChI=1S/C29H28N8O/c1-18-25(21-8-9-24(38-3)31-16-21)36-28(34-18)29(2)10-12-37(13-11-29)27-22-14-23(35-26(22)32-17-33-27)20-6-4-19(15-30)5-7-20/h4-9,14,16-17H,10-13H2,1-3H3,(H,34,36)(H,32,33,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent					Assay Description The c-kit mutant D816V (or kinase domain thereof) is an active kinase in AlphaScreen. IC50 values are determined with respect to inhibition of c-Kit ...				US Patent US9771369 (2017) BindingDB Entry DOI: 10.7270/Q24J0H7Q
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM342340 (4-[4-[4-[5-(6-methoxy-3-pyridyl)-4- methyl-1H-imid...) Show SMILES COc1ccc(cn1)-c1[nH]c(nc1C)C1(C)CCN(CC1)c1ncnc2[nH]c(cc12)-c1ccc(cc1)C#N Show InChI InChI=1S/C29H28N8O/c1-18-25(21-8-9-24(38-3)31-16-21)36-28(34-18)29(2)10-12-37(13-11-29)27-22-14-23(35-26(22)32-17-33-27)20-6-4-19(15-30)5-7-20/h4-9,14,16-17H,10-13H2,1-3H3,(H,34,36)(H,32,33,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent					Assay Description Assays for biochemical cell-based activity of c-kit kinase are known in the art, for example, as described in U.S. Pat. Nos. 7,498,342 and 7,846,941,...				US Patent US9771369 (2017) BindingDB Entry DOI: 10.7270/Q24J0H7Q
					More data for this Ligand-Target Pair