BDBM342434 5-chloro-4-(cyclohexylmethoxy)-2-fluoro-N-(methylsulfonyl)benzamide::US9771376, Example 21
SMILES: CS(=O)(=O)NC(=O)c1cnc(OCC23CC4CC5(CC(C5)(C4)C2)C3)c(Cl)c1
InChI Key: InChIKey=XHHQCYBSLDIPNZ-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human)) | BDBM342434 (5-chloro-4-(cyclohexylmethoxy)-2-fluoro-N-(methyls...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 106 | n/a | n/a | n/a | n/a | n/a | n/a |
GENENTECH, INC.; XENON PHARMACEUTICALS INC. US Patent | Assay Description The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ... | US Patent US9771376 (2017) BindingDB Entry DOI: 10.7270/Q2W0983R | |||||||||||
More data for this Ligand-Target Pair |