BDBM34352 2-(morpholin-4-ylthio)-1H-benzimidazole::4-(1H-benzimidazol-2-ylsulfanyl)morpholine::4-(1H-benzimidazol-2-ylthio)morpholine::MLS000084795::SMR000019141::cid_3236390

SMILES: C1CN(CCO1)Sc1nc2ccccc2[nH]1

InChI Key: InChIKey=GJTNIQIZAQUOJI-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 34352   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM34352 (2-(morpholin-4-ylthio)-1H-benzimidazole | 4-(1H-be...) Show SMILES C1CN(CCO1)Sc1nc2ccccc2[nH]1 Show InChI InChI=1S/C11H13N3OS/c1-2-4-10-9(3-1)12-11(13-10)16-14-5-7-15-8-6-14/h1-4H,5-8H2,(H,12,13)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	8.0	23
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description A fluorescence resonance energy transfer assay is developed in 96-well and 384-well microplate formats with robotic manipulation to enable high-throu...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2H70D5W
					More data for this Ligand-Target Pair
MPI protein (Homo sapiens (Human))	BDBM34352 (2-(morpholin-4-ylthio)-1H-benzimidazole | 4-(1H-be...) Show SMILES C1CN(CCO1)Sc1nc2ccccc2[nH]1 Show InChI InChI=1S/C11H13N3OS/c1-2-4-10-9(3-1)12-11(13-10)16-14-5-7-15-8-6-14/h1-4H,5-8H2,(H,12,13)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	7.4	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description The purpose of this assay is to identify non-competititve inhibitors of human PMI. This is accomplished by using a G6PD- NADPH-coupled assay. In the ...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2CF9NFM
					More data for this Ligand-Target Pair
eukaryotic translation initiation factor 4 gamma, 1 isoform 4 (Homo sapiens (Human))	BDBM34352 (2-(morpholin-4-ylthio)-1H-benzimidazole | 4-(1H-be...) Show SMILES C1CN(CCO1)Sc1nc2ccccc2[nH]1 Show InChI InChI=1S/C11H13N3OS/c1-2-4-10-9(3-1)12-11(13-10)16-14-5-7-15-8-6-14/h1-4H,5-8H2,(H,12,13)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	2.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation NIH Molecular Libraries Screening Centers Network [MLSC...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2RN3686
					More data for this Ligand-Target Pair
mevalonate kinase (Streptococcus pneumoniae D39)	BDBM34352 (2-(morpholin-4-ylthio)-1H-benzimidazole | 4-(1H-be...) Show SMILES C1CN(CCO1)Sc1nc2ccccc2[nH]1 Show InChI InChI=1S/C11H13N3OS/c1-2-4-10-9(3-1)12-11(13-10)16-14-5-7-15-8-6-14/h1-4H,5-8H2,(H,12,13)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	>1.00E+7	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC Curated by PubChem BioAssay					Assay Description Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q27P8WSS
					More data for this Ligand-Target Pair
mevalonate kinase (Streptococcus pneumoniae D39)	BDBM34352 (2-(morpholin-4-ylthio)-1H-benzimidazole | 4-(1H-be...) Show SMILES C1CN(CCO1)Sc1nc2ccccc2[nH]1 Show InChI InChI=1S/C11H13N3OS/c1-2-4-10-9(3-1)12-11(13-10)16-14-5-7-15-8-6-14/h1-4H,5-8H2,(H,12,13)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	1.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC Curated by PubChem BioAssay					Assay Description Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q23X852V
					More data for this Ligand-Target Pair
mevalonate kinase (Streptococcus pneumoniae D39)	BDBM34352 (2-(morpholin-4-ylthio)-1H-benzimidazole | 4-(1H-be...) Show SMILES C1CN(CCO1)Sc1nc2ccccc2[nH]1 Show InChI InChI=1S/C11H13N3OS/c1-2-4-10-9(3-1)12-11(13-10)16-14-5-7-15-8-6-14/h1-4H,5-8H2,(H,12,13)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	1.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC Curated by PubChem BioAssay					Assay Description Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2CF9NG2
					More data for this Ligand-Target Pair