BDBM343753 US9777008, Compound 47

SMILES: OC(COc1ccc(cc1)C1CCCNC1)CN1CCc2ccccc2C1

InChI Key: InChIKey=HUPUCRUHTCXPRQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 343753   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PRMT5/MEP50 Enzyme (Homo sapiens (Human))	BDBM343753 (US9777008, Compound 47) Show SMILES OC(COc1ccc(cc1)C1CCCNC1)CN1CCc2ccccc2C1 Show InChI InChI=1S/C23H30N2O2/c26-22(16-25-13-11-18-4-1-2-5-21(18)15-25)17-27-23-9-7-19(8-10-23)20-6-3-12-24-14-20/h1-2,4-5,7-10,20,22,24,26H,3,6,11-17H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US9777008 (2017) BindingDB Entry DOI: 10.7270/Q26975QQ
					More data for this Ligand-Target Pair