BDBM344115 N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl]-5-(2-hydroxyethyl)-4-oxo-4,5,6,7-tetrahydrofuro[3,2-c]pyridine-3-carboxamide::US9777020, Example 9

SMILES: CCOc1nc(ccc1NC(=O)c1coc2CCN(CCO)C(=O)c12)N1CCN(CC1)C(C)=O

InChI Key: InChIKey=BXLZREQIIYWPFZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344115   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM344115 (N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...) Show SMILES CCOc1nc(ccc1NC(=O)c1coc2CCN(CCO)C(=O)c12)N1CCN(CC1)C(C)=O Show InChI InChI=1S/C23H29N5O6/c1-3-33-22-17(4-5-19(25-22)27-10-8-26(9-11-27)15(2)30)24-21(31)16-14-34-18-6-7-28(12-13-29)23(32)20(16)18/h4-5,14,29H,3,6-13H2,1-2H3,(H,24,31)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent									US Patent US9777020 (2017) BindingDB Entry DOI: 10.7270/Q2T155R7
					More data for this Ligand-Target Pair